Lissa studied at the Avni Institute in Tel Aviv, dedicating herself to the arts with a focus on painting, sculpture, and cinema. This period was crucial in shaping her artistic voice. The combination of her diverse educational background and her interests in gymnastics and science profoundly impacts her work. She is particularly drawn to exploring matter at a molecular level and capturing dynamic states. This blend of academic and personal interests has been instrumental in her development as a professional artist.

Lissa has exhibited her artwork at the prestigious Centaur Art Gallery in Las Vegas; Gallery 612; and her own gallery, The Messengers Art Gallery in Santa Monica. A notable project was her collaboration with Michael Kors, during which she painted on the brand's bags at a live event, blending art with high-end fashion. Recently, she participated in Context Art Miami 2023, held concurrently with Miami Art Basel; the SuperFine Los Angeles Art Fair; and launched her own apparel line, Loren Marie, merging her art with fashion design.